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  • Eric I Mitchell MD MA FAC

Just Like: Just Like Vitamin CBD™



Vitamins have three characteristics: They're natural components of our food sources; usually present in very small amounts. They're essential for normal physiologic function (e.g., growth, reproduction, cell regeneration, etc.). When absent from our diet, they will cause a specific deficiency just like vitamin CBD.


Vitamins may be fat soluble (vitamins A, D, E, and K) just like vitamin CBD or water-soluble (B vitamins and vitamin C). Vitamin A is a critical player in the growth and development of your heart, lungs, kidneys, and other organs. It’s also important for maintaining good vision and a proper-running immune system, just like what Vitamin CBD does for our body. Vitamin A also is a powerful antioxidant, just like vitamin CBD™, so it’ll help to protect cells from the damage of free radicals.


Some diseases caused by vitamin deficiencies, such as scurvy, have been recognized since sailors sailed the seas, but it was only in the 20th century that nutritional studies identified the chemical structures of many of these essential compounds. In 1932, Vitamin C was found to be necessary to prevent scurvy. Humans have to get vitamin C from a food source because we’re unable to synthesize it on our own. Vitamin C is an important antioxidant. It is also important for the formation of collagen and supports immune function, just like Vitamin CBD™ which is both endogenous and supplemental when taken as a phytocannabinoid. (4)


Vitamin D and Vitamin CBD™ do many of the same things: C27H44O is Vitamin D molecular structure and C21H30O2 is Vitamin CBD™ molecular structure. (6) Research has shown that the hemp plant itself has a large amount of Vitamin D but it is not a replacement from a dietary standpoint.


Vitamin E is actually the collective name for a group of compounds known for their powerful antioxidant properties just like Vitamin CBD™. It has also been shown beneficial for helping prevent various types of cancers in animal models just like Vitamin CBD. (7)


When the body consumes tryptophan, one of our essential amino acids, it converts it to niacin, a B vitamin that plays a role in the neurotransmitter serotonin. This role isn’t only relevant to things like depression (as anti-depressants often work by increasing serotonin levels), but it also helps modulate sleep just like Vitamin CBD™ Modulation of sleep is one of the most frequent uses for Vitamin CBD™.


Vitamin CBD™ is a natural chemical derived from the cannabis plant. The compound belongs to a classification known as cannabinoids, which are found both in cannabis (phytocannabinoids) and the human body (endocannabinoids). Vitamin CBD™ has become incredibly well-known in recent years for its ability to assist in the treatment of symptoms of an entire host of illnesses and health conditions as outlined above. This is commonly referred to as body balance or homeostasis between mind and body.


Of particular interest are the antioxidant, anti-inflammatory, neuroprotective, and anti-convulsant actions of this cannabinoid known as CBD. Vitamin CBD™ is a more potent neuroprotective antioxidant than both vitamin C and vitamin E. Higher doses of the cannabinoid are postulated to be therapeutic for various psychiatric disorders such as schizophrenia and dementia. Research in the areas of diabetes and nausea also show potential. (3)



CBD is known as a safe and natural part of the phytocannabinoid system with virtually zero deaths associated with its use. Research has rated the herb as the least dangerous substance when compared to substances such as alcohol and nicotine in regards to toxicity. The known risks associated with CBD use are most often related to the psychoactive activity of hemp. THC, the psychoactive constituent within the hemp plant, has been linked to agitating mental conditions in some people. however, has little or no THC (less than 0.3% THC) and has actually been shown to be antipsychotic.


Vitamin CBD™ is generally regarded as safe (GRAS). Vitamin CBD™. exerts its effects on the body in a myriad of ways, acting indirectly upon the CB1 and CB2 receptors of the endocannabinoid system. It also interacts with serotonin, vanilloid, GPR55, and PPARs receptors. Hemp and it's by-products historically have been in the world’ s food chain for thousands of years. Just like vitamin CBD™


The negative is that the endocannabinoid system discovered in 1992 still is not being taught in our medical schools because of Federal prohibition under the Controlled Substances Act of 1970 (CSA). However, December 20, 2018, is when the Farm Bill of 2018 was signed into law removing Hemp with less than 0.3% THC from the CSA. This resin from the female hemp plant and all its cannabinoids can now take its place in the vitamin arena. (1, 2)


A 2017 review published within the journal Cannabis and Cannabinoid Research documents the safety and side effects of Vitamin CBD. The review discusses the use of CBD within numerous clinical studies, most of them regarding epilepsy and psychotic disorders. The most common side effects of Vitamin CBD appear to be tiredness, diarrhea, and changes in both weight and appetite.

Another review, this time published in the journal Current Drug Safety, shows that Vitamin CBD™ has no adverse effects upon physiological parameters including heart rate, blood pressure, body temperature, psychological and psychomotor functions, gastrointestinal transit, and food intake.


Until the endocannabinoid system (ECS) was recently unchained from its narcotic prohibition allowing CBD, which mirrors multiple vitamins as outlined above, it was unable to take its rightful space as a vitamin. I have drawn multiple comparisons of multiple vitamins to parallel what we find in the phytocannabinoid known as cannabidiol (CBD). Just like Vitamin CBD™.



REFERENCES


1. Clinical endocannabinoid deficiency (CECD): can this concept explain therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions?

Neuro Endocrinol Lett. 2008 Apr;29(2):192-200.


2. Iffland K, Grotenhermen F. An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies. Cannabis Cannabinoid Res. 2017;2(1):139-154. Published 2017 Jun 1. doi:10.1089/can.2016.0034


3. El-Remessy, A. B., Khalil, I. E., Matragoon, S., Abou-Mohamed, G., Tsai, N. J., Roon, P., Caldwell, R. B., Caldwell, R. W., Green, K., … Liou, G. I. (2003). Neuroprotective effect of (-)Delta 9-tetrahydrocannabinol and cannabidiol in N-methyl-D-aspartate-induced retinal neurotoxicity: involvement of peroxynitrite. The American Journal of Pathology, 163(5), 1997-2008.


4. J Neuroimmune Pharmacol.2015 Jun;10(2):193-203. doi: 10.1007/s11481-015-9615-z. Epub 2015 Jun9


5. Bergamaschi MM1, Queiroz RH, Zuardi AW, Crippa JA. Curr Drug Saf. 2011 Sep 1;6(4):237-49.

Safety and side effects of cannabidiol, a Cannabis sativa constitute


6. J Bone Miner Res. 2015 Oct;30(10):1905-13. doi: 10.1002/jbmr.2513. Epub 2015 May 10.

Cannabidiol, a Major Non-Psychotropic Cannabis Constituent Enhances Fracture Healing and Stimulates Lysyl Hydroxylase Activity in Osteoblasts. https://www.ncbi.nlm.nih.gov/pubmed/25801536#


7. Ramer R, Bublitz K, Freimuth N, et al.: Cannabidiol inhibits lung cancer cell invasion and metastasis via intercellular adhesion molecule-1. FASEB J 26 (4): 1535-48, 2012. [PUBMED Abstract]. Safety and side effects of cannabidiol, a Cannabis sativa constituent. Curr Drug Saf. 2011 Sep 1;6(4):237-49.


8. Medicinal plants and bone healing. Singh V. Natl J Maxillofac Surg. 2017 Jan-Jun; 8(1):4-11.


9. Cannabidiol in medicine: a review of its therapeutic potential in CNS disorders. Scuderi C, Filippis DD, Iuvone T, Blasio A, Steardo A, Esposito G. Phytother Res. 2009 May; 23(5):597-602.








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